Result Interpretation

ROTEM® delta

The assessment of the ROTEM® analysis is carried out along the time axis (from left to right): A disturbed activation of coagulation is indicated by a prolonged clotting time (CT). As causes, a factor deficiency or a heparin effect should be considered. The comparison of INTEM and HEPTEM allows for a specific detection of a heparin effect. An abnormal clot formation is indicated by a prolonged clot formation time (CFT) and/or a reduced clot firmness (MCF). The CFT is thereby influenced more strongly by a clot polymerization disorder than the MCF. A prolonged CFT, with at the same time normal MCF, therefore indicates a polymerization disorder, whereas a reduced MCF with a normal CFT indicates a deficiency of clottable substrate (fibrinogen and / or platelets).Fibrinolysis is detected by the lysis of the clot (ML > 15%) or by the finding of a better clot formation (shorter CFT, greater MCF) in APTEM as compared to EXTEM. Several centers already use (in massive bleeding) a shortening of the CT in APTEM, as compared to EXTEM, as a trigger for an antifibrinolytic drug administration.

Normal patient

Result interpretation normal patient

Platelet deficiency

Result interpretation platelet deficiency

Fibrinogen deficiency

Result interpretation fibrinogen deficiency

Hyperfibrinolysis

Result interpretation hyperfibrinolyse

Heparin influence

Result interpretation heparin influence

ROTEM 101

Learn the basics of interpretation and clinical application of thromboelastometry with this training video: